Formulasi NLC-Stick Ekstrak Bunga Telang (Clitoria ternatea L.) Dengan Variasi Konsentrasi Shea Butter dan Asam Stearat
DOI:
https://doi.org/10.32734/idjpcr.v7i1.16719Keywords:
NLC-Stick, telang extract, shea butter, stearic acidAbstract
NLC of telang flower extract has an effect as a sunscreen to protect the skin from sunlight. Stick preparation in NLC formulation can facilitate the use of sunscreen. This study aims to determine and compare variations in the concentration of Shea Butter (as a Base) and stearic acid (as a Harding Agent) and obtain the results of physical evaluation of variations in the concentration of Shea butter and Stearic Acid. NLCs of telang flower extract were formulated into formulas with varying concentrations of shea butter and stearic acid in the ratio of 80:20; 50:50; 20:80. Furthermore, the physical properties of NLC-Stick of bay flower extract were evaluated, including organoleptic test, homogeneity test, pH test, melting time test, and spreadability test. The results showed that the optimal variation of shea butter and stearic acid concentration was 50:50. The optimum formula of NLC-Stick of telang flower extract has a colour like the active substance, solid shape, soft aroma, homogeneous, pH of 4.56 ± 0.3, melting time test of 21 minutes, and spreadability test of 3 cm. NLC-Stick with varying concentrations of shea butter:stearic acid (50:50) has a physical evaluation that meets the stick requirements.
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References
Purwanto UM, Aprilia K, Sulistyani. Antioxidantsanr activity of telang (Clitoria ternatea L.) Extract in inhibiting lipid peroxidation. Current Biochemistry. 2022; 9(1): 26 – 37.
Prasiddha IJ, Laeliocattleya RA, Estiasih T, Maligan JM. Potensi Senyawa Bioaktif Rambut Jagung (Zea mays L.) Untuk Tabir Surya Alami: Kajian Pustaka. Jurnal Pangan dan Agroindustri. 2016; 4(1): 40 – 45.
Raniah ZH, Hidayat AF, Priani SE. Kajian Pengembangan Sistem Nanopartikel Berbasis Lipid Sebagai Pembawa Zat Aktif Pada Sediaan Tabir Surya. Bandung Conference Series: Pharmacy. 2022; 2(2): 14 – 23.
Puspitasari D, Pratimasari D, Andriani D. Penentuan Nilai SPF (Sun Protection Factor) Krim Ekstrak Etanol Bunga Telang (Clitoria Ternatea) Secara In Vitro Menggunakan Metode Spektrofotometri. Jurnal Insan Farmasi Indonesia. 2019. 2(1):118–25.
Yati K, Dwita LP, Oktaviana L, Gantini SN. Perbandingan Penggunaan Minyak Zaitun, Vco Dan Minyak Jojoba Terhadap Sifat Fisik Balsem Stick Jintan Hitam (Nigella sativa L.) Dan Aktivitas Antiinflamasi Subakut. Prosiding Kolokium Doktor dan Seminar Hasil Penelitian Hibah. 2019; 1(1): 563 – 572.
Astuti R, Taswin M, Risdayanti. Formulasi Sediaan Aromaterapi Stik Dari Campuran Minyak Lavender, Jeruk Manis Dan Bergamot Dengan Veriasi Konsentrasi Asam Stearat Sebagai Harding Agent. Jurnal Kesehatan Poltekkes Palembang. 2021; 16(1): 22–28.
Rosli NA, Hasham R, Aziz AA, Aziz R. Formulation And Characterization Of Nanostructured Lipid Carrier Encapsulated Zingiber Zerumbet Oil Using Ultrasonication Technique. Journal Of Advanced Research In Applied Mechanics. 2015; 11(1): 16 – 23.
Febriani Y, Hanafiah A, Fahriyah A. Pembuatan Sediaan Pelembut Tumit Bentuk Batang (Stick) Kombinasi Ekstrak Buah Alpukat (Persea Americana Mill.) Dengan Serbuk Getah Buah Pepaya (Carica Papaya Linn.). Indonesian Journal Of Pharmaceutical Science And Technology. 2015 ;4(1) :1 – 8.
Athaillah, Lianda SO. Formulasi Dan Evaluasi Sediaan Balsem Stik Dari Oleoresin Jahe Merah (Zingiber officinale Rosc) Sebagai Pereda Nyeri Otot Dan Sendi. Journal Of Pharmaceutical And Sciences (JPS). 2021; 4(1): 34 – 40.
Ramadani MF, Malahayati S, Mahdiyah D. Formulasi dan Evaluasi Sediaan Blush on Stick Ekstrak Umbi Bit (Beta Vulgaris L) Sebagai Antioksidan. Jurnal Integrasi Kesehatan & Sains. 2023; 5(1): 45 – 51.
Voigt R. Buku Pelajaran Teknologi Farmasi. 5th Ed. Noerono S, Editor. Yogyakarta: UGM Press; 1995.
Nurapni D, Risna K, Musa K, Ardianti R, Dalimunthe Y, dkk. Literatur Review Analisis Perbandingan Uji Waktu Leleh Suppositoria Dari Berbagai Basis. INNOVATIVE. 2023; 3(2): 10125 - 10138.
Oluwaseyi Israel M. Effects of Oral and Topical Use of the Oil from the Nut of Vitellaria paradoxa. J Nutr Food Sci. 2014;04(06).
Listiyana A, Muti’ah R, Suryadinata A, Farida D, Salsabilla R. Pengembangan Sistem Nanostructured Lipid Carrier (NLC) Daun Chrysanthemum Cinerariifolium (Trev.) Vis Dengan Variasi Konsentrasi Lipid. Journal Of Islamic Medicine. 2020; 4(2): 86 – 97.
Saefafuna Y, Pratiwi E, Salmadea K, Ady K, Reejeki S. Formulasi Sediaan Deodorn Stick Dengan Tawas. Farmasi STIKes Bhakti Mandala Husada. 2019; 1 – 4.
R. Fitri, H. D. Syahputra, N. Nasri, V. E. Kaban, and Z. Rani, ‘Formulation of a biocellulose mask containing the essence of Aloe vera (L.) Burm. f combination with vitamin E as anti-aging’, Sci. Pharm. Sci., no. 6 (40), pp. 36–42, 2022.
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