Correlation between Neutrophil to Lymphocyte Ratio (NLR) and D-Dimer In Patients Covid-19 with Diabetes

Abstract

Abstract:

Background: The neutrophil to lymphocyte ratio (NLR) has been proposed as an infammatory biomarker. Tujuan penelitian adalah menilai hubungan antara NLR dan D-dimer pada pasien Covid-19 dengan diabetes.

Method: This is a retrospective descriptive and analytical study carried out at NLR, blood rutin and D-dimer, FPG, and PPG levels of COVID-19 patients with comorbid in H. Adam Malik Medan, Indonesia, from May 19, 2020, to Juny 08, 2021. The data were collected by cheek list, using electronic medical records. The data included age, gender, medical history, comorbidity with diabetics, and ward and ICU admission. All these cases of COVID-19 have been confirmed in the laboratory by Real-Time Reverse Transcription Polymerase Chain Reaction (RTPCR).

Results: There were 163 COVID-19 patients with diabetes consisting FPG 241.65±122.23 mg/dl, PPG 286.01±123.92 mg/dl, and HbA1c 9.49±2.41%. There is a significant correlation between NRL and hemoglobin, white blood cells, platelets, neutrophils, and D-dimers (all, p<0.001*).

Conclusion: Diabetes is the commonest comorbidity in COVID-19 patients, and NLR and the others inflammatory assessment have reliable parameters for assessing and evaluating the prognosis of the COVID-19 patients as well as an accurate and practical coagulation parameter for predicting mortality.