Pharmacotherapy of Hypertension in Chronic Dialysis Patients in USU Hospital Medan

Abstract

Background: Hypertension is closely related to chronic kidney disease (CKD) patients because hypertension can be a cause or a result of hemodialysis (HD). The way that can be done to control blood pressure is the administration of antihypertensive drugs. The use of antihypertensive drugs in CKD on HD patients in hospitals is needed as an evaluation material in terms of the accuracy and optimization of drug administration. This study aims to know the administration pattern of antihypertensive drugs used by the HD unit in USU Hospital Medan.

Method: Descriptive statistics were used to present the antihypertensive drug prescription pattern of CKD in HD patients. This study used data in the form of medical records and also direct interviews with patients and nurses of the HD Unit at USU Hospital in 2022.

Results: The most common single drug antihypertensive used was Calcium Channel Blocker (CCB) as amlodipine 67.4% either alone or in combination. The most common 2 drugs antihypertensive combination were Angiotensin Receptor Blocker (ARB) as candesartan and CCB as amlodipine 19.5%.

Conclusion: The most common single drug antihypertensive used was CCB, and the most common drugs antihypertensive in combination 2 drugs were CCB and ARB.