SCRIPTA SCORE Scientific Medical Journal https://talenta.usu.ac.id/scripta <p style="text-align: justify;">SCRIPTA SCORE Scientific Medical Journal is a medical student scientific journal from SCORE PEMA FK USU (Standing Committee on Research Exchange of Student Government Faculty of Medicine, University of North Sumatra). SCRIPTA SCORE Scientific Medical Journal is one of the SCORE PEMA FK USU icons that works together with many reviewers to support the quality and validity of a manuscript. Initially, in 2009, SCORE PEMA FK USU formed a medical student journal with the name of JIMKI (Indonesian Medical Student Scientific Journal). Then for some reason, the management of JIMKI has been moved to BAPIN-ISMKI authority (National Scientific Analysis and Development Agency-Indonesian Medical Student Senate Association). Subsequently, in 2011 a new journal was formed with the name of SCRIPTA by SCORE PEMA FK USU. Since 2016 until now, the SCRIPTA SCORE Scientific Medical Journal was published in 1 volume with 2 numbers every year in February and August that can be accessed <a href="https://drive.google.com/folderview?id=1VmMl2etWqCIEXopvDuGZn6OzSKsyYTk7">here</a>. SCRIPTA SCORE Scientific Medical Journal consists of 5-8 manuscripts with types of manuscripts such as research, literature review, and case reports in each volume. Publications from the SCRIPTA SCORE Scientific Medical Journal can be accessed offline (pISSN <a href="https://portal.issn.org/resource/ISSN-L/2088-8686">2088-8686</a>) on printed SCRIPTA SCORE Scientific Medical Journal magazine or online (eISSN <a href="https://issn.brin.go.id/terbit/detail/1561988158">2686-0864</a>) through the SCRIPTA SCORE Scientific Medical Journal (<a href="https://talenta.usu.ac.id/scripta">https://talenta.usu.ac.id/scripta</a>)</p> en-US <div id="coptf"> <p align="justify">Authors who publish with SCRIPTA SCORE Scientific Medical Journal agree to the following terms:</p> <ol> <li class="show"><span lang="EN-GB">Authors retain copyright and grant SCRIPTA SCORE Scientific Medical Journal right of first publication with the work simultaneously licensed under a <a title="CC BY NC" href="http://creativecommons.org/licenses/by-nc/4.0/" target="_self">Creative Commons Attribution-NonCommercial License</a> that allows others to remix, adapt, build upon the work non-commercially with an acknowledgment of the work’s authorship and initial publication in SCRIPTA SCORE Scientific Medical Journal.</span></li> <li class="show">Authors are permitted to copy and redistribute the journal's published version of the work non-commercially (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in SCRIPTA SCORE Scientific Medical Journal.</li> </ol> </div> scripta@usu.ac.id (Liza Chairina Balchya Lubis) scripta@usu.ac.id (Lira Haniya Sinta Beru Singarimbun) Thu, 27 Feb 2025 00:33:21 +0700 OJS 3.2.1.5 http://blogs.law.harvard.edu/tech/rss 60 Front & Back Matter https://talenta.usu.ac.id/scripta/article/view/20062 Copyright (c) 2025 https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/20062 Thu, 27 Feb 2025 00:00:00 +0700 The Combination of Surgical Excision with Debulking Technique and Intralesional Triamcinolone Acetonide Injection in the Management of Keloid https://talenta.usu.ac.id/scripta/article/view/17727 <p style="font-weight: 400;"><strong>Abstract</strong>. <strong>Background</strong>: Keloid is a fibroproliferative disorder of the dermis resulting from abnormal wound healing, characterized by excessive collagen deposition, thickened and highly vascularized dermis, and abundant infiltration of inflammatory cells.The highest incidence of keloid occurs in individuals during their second decade of life. <strong>Case Ilustartion</strong>: A 16-year-old female presented to the Dermatology and Venereology Clinic at Prof. Chairuddin P. Lubis Hospital, Medan, with the chief complaint of a lump on the front and back of her left earlobe accompanied by itching for the past three years. Initially, 4 years ago, the patient complained of itching after ear piercing. Over time, a lump appeared at the site of the piercing. The lump was reported to have gradually increased in size over the past 2 years. Dermatological examination, there was a solitary erythema nodule with firm boundaries, with a spongy solid consistency, oval round shape and size 1.4x1.3x0.9 cm, regular edges, smooth surface in the region of the anterior auricularis lobule sinistra and posterior auricularis lobule sinistra. The patient was diagnosed with keloid. The patient was then planned for surgical excision with debulking technique and intralesional triamcinolone acetonide injection. <strong>Discussion</strong>: It is stated in the literature that combination treatment is the optimal strategy and from most studies it has been found that surgical excision combined with steroid injection shows a recurrence rate of less than 50%. <strong>Conclusion: </strong>Keloid treatment should be done in combination to reduce recurrence. </p> <p style="font-weight: 400;"> </p> <p style="font-weight: 400;"><strong>Abstrak</strong></p> <p style="font-weight: 400;">Keloid merupakan kelainan fibroproliferatif pada dermis akibat penyembuhan luka yang tidak normal, ditandai dengan deposisi kolagen yang berlebihan, penebalan dan vaskularisasi dermis yang tinggi, serta infiltrasi sel inflamasi yang melimpah. Insidensi keloid tertinggi terjadi pada individu pada usia dekade kedua.</p> <p style="font-weight: 400;"> <strong>Ilustrasi Kasus:</strong> Seorang perempuan berusia 16 tahun datang ke Poliklinik Dermatologi dan Venereologi RS Prof. Chairuddin P. Lubis Medan dengan keluhan utama adanya benjolan di bagian depan dan belakang daun telinga kiri disertai rasa gatal sejak tiga tahun yang lalu. Awalnya, 4 tahun lalu, pasien mengeluh gatal setelah tindik telinga. Seiring waktu, benjolan muncul di lokasi penindikan. Benjolan tersebut dilaporkan bertambah besar secara bertahap selama 2 tahun terakhir. Pada pemeriksaan dermatologi terdapat bintil eritema soliter berbatas tegas, konsistensi padat seperti spons, bentuk bulat lonjong dan ukuran 1,4x1,3x0,9 cm, tepi teratur, permukaan licin pada daerah lobulus aurikularis anterior sinistra dan lobulus aurikularis posterior sinistra. Pasien didiagnosis dengan keloid. Pasien kemudian direncanakan untuk dilakukan eksisi bedah dengan teknik debulking dan injeksi triamcinolone acetonide intralesi. <strong>Pembahasan:</strong> Penatalaksanaan kombinasi merupakan strategi yang optimal dan sebagian besar penelitian ditemukan bahwa eksisi bedah yang dikombinasikan dengan injeksi steroid menunjukkan angka kekambuhan &gt;50%. <strong>Kesimpulan:</strong> Pengobatan keloid sebaiknya dilakukan secara kombinasi untuk mengurangi kekambuhan.</p> Riana Miranda Sinaga, Desy Sahara Putri S Copyright (c) 2025 Riana Miranda Sinaga, Desy Sahara Putri S https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/17727 Thu, 27 Feb 2025 00:00:00 +0700 Xanthelasma Palpebrarum In A Young Adult Male Patient https://talenta.usu.ac.id/scripta/article/view/17803 <p><strong>ABSTRACT</strong></p> <p><strong>Background:</strong> Xanthelasma palpebrarum is a most common form of xanthoma characterized as lesion with yellowish colour, flat, soft, and mostly found in medial corner of eyelids. Most cases of xanthelasma are associated with hyperlipidemia. <strong>Case Reports:</strong> A male aged 37 presented with yellow patches on both upper eyelids since ±2 years ago. Vital sign within normal limid. Dermatological examination found yellowish plaques with clear boundaries sized 0.5 cm located on medial canthus of the supraorbital dextra and sized 1 cm located on medial canthus of the supraorbital sinistra. Laboratory test showed that hypercholesterolemia. The patient then underwent excision surgical procedure. <strong>Discussion:</strong> Xanthoma is a plaque consisted abnormal deposition of lipid and foam cells. Generally, this condition is found in aged 40–60 years old. The condition is found more in females than males, on superior palpebrae as the most common location. Diagnosis is established based on history and dermatological evaluation. The aim of xanthelasma management is mostly cosmetic-related. Elliptical or fusiform excision is the most method applied. <strong>Conclusion: </strong>A 37 years old male with xanthelasma palpebrarum on bilateral upper eyelids with hypercholesterolemia was treated with surgical excision. The surgical wound appeared well later on the 6th days and a month post-surgery.</p> <p style="font-weight: 400;"><strong>Latar Belakang: </strong>Xantelasma palpebrarum merupakan bentuk xantoma yang paling umum dengan lesi berwarna kekuningan, datar, lunak, dan sebagian besar terletak di sudut medial palpebra. Sering dikaitkan dengan hiperlipidemia. <strong>Laporan Kasus: </strong>Seorang laki-laki 37 tahun datang dengan bercak kekuningan pada kedua sudut kelopak mata atas sejak ±2 tahun lalu. Tanda vital dalam batas normal. Pemeriksaan dermatologis ditemukan plak berwarna kekuningan, dengan diameter berukuran 0,5 cm berbatas tegas pada regio kantus medial supraorbital dekstra dan 1 cm berbatas tegas pada regio kantus medial supraorbital sinistra. Pemeriksaan laboratorium menunjukkan kolesterol total 215 mg/dL, HDL 45 mg/dL, LDL 126 mg/dL, dan trigliserida 110 mg/dL. Pasien kemudian direncanakan untuk dilakukan bedah eksisi. <strong>Diskusi: </strong>Xantoma adalah plak yang terdiri dari endapan lipid abnormal dan sel busa. Umumnya kondisi ini muncul pada usia 40-60 tahun, ditemukan lebih banyak pada perempuan dibandingkan dengan laki-laki dan palpebra superior sebagai lokasi tersering. Diagnosis umumnya ditegakkan berdasarkan anamnesis dan pemeriksaan dermatologis. Penatalaksanaan xantelasma ditujukan untuk mengatasi gangguan kosmetik. Eksisi elips merupakan metode yang paling banyak digunakan. <strong>Kesimpulan: </strong>Seorang pria 37 tahun dengan xantelasma palpebrarum pada palpebra superior bilateral dengan hiperkolesterolemia ditangani dengan bedah eksisi. Luka tampak baik saat kontrol 6 hari dan satu bulan pasca tindakan.</p> <p style="font-weight: 400;"> </p> <p> </p> Riana Miranda Sinaga, Nahrisyah Copyright (c) 2025 Riana Miranda Sinaga, Nahrisyah https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/17803 Thu, 27 Feb 2025 00:00:00 +0700 An In-depth Review of Cutaneous Necrotizing Venulitis: Clinical and Pathological Perspective https://talenta.usu.ac.id/scripta/article/view/17896 <p><strong>Background: </strong>Cutaneous Necrotizing Venulitis (CNV) is a complex multisystem disorder primarily affecting small skin vessels, particularly postcapillary venules. <strong>Objective: </strong>This article aims to discuss about cutaneous necrotizing venulitis (CNV). <strong>Methods: </strong>This article was written by reviewing book and articles related with cutaneous necrotizing venulitis (CNV) which are obtained from several search engines such as Pubmed, Science Direct, and Google Scholar. <strong>Discussion: </strong>CNV usually manifests as palpable purpura on the skin and may also involve multiple organ systems, including the kidneys, gastrointestinal tract, pericardium, and nervous system. The etiology of CNV remains incompletely understood but is often associated with infections, drug reactions, systemic inflammatory diseases, and malignancies. Clinical manifestation of CNV is mainly palpable purpura, which is red purpura that does not disappear when the skin is pressed. Other lesions such as erythematous macules, papulonodular lesions, urticaria, angioedema, pustules, hemorrhagic vesicles and bullae, necrosis, ulcers, subcutaneous edema and livedo reticularis can also be found in CNV cases. <strong>Conclusion</strong>: Cutaneous Necrotizing Venulitis (CNV) is a complex disease primarily affecting the skin and mucous membranes. Diagnosis of CNV involves clinical evaluation and histopathological examination. Treatment strategies of CNV aim to address underlying triggers, manage systemic involvement, and suppress inflammatory responses using topical and systemic therapies such as corticosteroids, NSAIDs, and immunosuppressive agents. Treatment strategies of CNV aim to address underlying triggers, manage systemic involvement, and suppress inflammatory responses using topical and systemic therapies such as corticosteroids, NSAIDs, and immunosuppressive agents and CNV often exhibits a favorable prognosis with appropriate management.</p> <p> </p> <p><strong>Latar Belakang: </strong><em><span style="font-weight: 400;">Cutaneous necrotizing venulitis</span></em><span style="font-weight: 400;"> (CNV) adalah gangguan multisistem yang kompleks, terutama menyerang pembuluh darah kecil di kulit, khususnya venul postkapiler</span><strong>. Tujuan: </strong><span style="font-weight: 400;">Artikel ini bertujuan untuk memberikan analisis mendalam mengenai patogenesis, manifestasi klinis, diagnosis, dan strategi pengobatan CNV</span><strong>. Metode: </strong><span style="font-weight: 400;">Artikel ini didasarkan pada tinjauan literatur dari berbagai sumber ilmiah yang relevan, termasuk jurnal dan buku yang diakses melalui PubMed, ScienceDirect, dan Google Scholar</span><strong>. Pembahasan: </strong><span style="font-weight: 400;">CNV biasanya bermanifestasi sebagai purpura teraba pada kulit dan dapat melibatkan berbagai sistem organ, termasuk ginjal, saluran gastrointestinal, perikardium, dan sistem saraf. Etiologi CNV masih belum sepenuhnya dipahami, tetapi sering dikaitkan dengan infeksi, reaksi obat, penyakit inflamasi sistemik, dan keganasan. Manifestasi klinis utama CNV adalah purpura teraba, yaitu purpura berwarna merah yang tidak menghilang saat kulit ditekan. Lesi lain yang dapat ditemukan pada kasus CNV meliputi makula eritematosa, lesi papulonodular, urtikaria, angioedema, pustula, vesikel dan bula hemoragik, nekrosis, ulkus, edema subkutan, serta livedo reticularis</span><strong>. Kesimpulan: </strong><span style="font-weight: 400;">Cutaneous necrotizing venulitis (CNV) adalah penyakit kompleks yang terutama mempengaruhi kulit dan selaput lendir. Diagnosis CNV melibatkan evaluasi klinis dan pemeriksaan histopatologi. Strategi pengobatan CNV bertujuan untuk mengatasi pemicu yang mendasari, mengelola keterlibatan sistemik, serta menekan respons inflamasi menggunakan terapi topikal dan sistemik, seperti kortikosteroid, NSAID, dan agen imunosupresif. CNV umumnya memiliki prognosis yang baik dengan penanganan yang tepat. </span></p> <p><strong>Keywords: </strong><span style="font-weight: 400;">angiitis nekrotikans, vaskulitis, venulitis, venulitis nekrotikans kutan</span></p> Cut Putri Hazlianda, Rima Rahmi Putri Harahap Copyright (c) 2025 Cut Putri Hazlianda, Rima Rahmi Putri Harahap https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/17896 Thu, 27 Feb 2025 00:00:00 +0700 A Review: How Metformin Improves the Prognosis for Coronavirus Disease-19 Patients with Hypertension? https://talenta.usu.ac.id/scripta/article/view/19644 Muhammad Mufaiduddin, Vito Etenio Ade Laryan, Saekhol Bakri Copyright (c) 2025 Muhammad Mufaiduddin, Vito Etenio Ade Laryan, Saekhol Bakri https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/19644 Thu, 27 Feb 2025 00:00:00 +0700 Breaking Through the Blister : Exploring Chronic Bullous Disease of Chidhood https://talenta.usu.ac.id/scripta/article/view/18780 <p><strong>Background :</strong> One of the autoimmune disease occurs on the first decade of life is Linear Immunoglobulin A Bullous Disease that initially referred to as Chronic Bullous Disease of Childhood is an infrequent and nonhereditary skin disorder defined by a linear accumulation of immunoglobulin A. The lesions present as clear or hemorrhagic vesicles (or both) or bullae that emerge from otherwise normal skin, occasionally accompanied by an erythematous or urticarial base. The bullae or vesicles are typically tense, vary in size, and often develop into annular or polycyclic plaques as a result of the lesions merging together. CBDC is a self-limiting disease, with most children experiencing recovery within two years of the symptom beginning, in some cases, the disease continues into puberty, but it is typically less severe than the initial eruption. <strong>Objective :</strong> This literature review aims to provide a comprehensive understanding of CBDC, including its pathogenesis, diagnosis and appropriate therapeutic approaches for managing the disease. <strong>Methods : </strong>Herein, using the key terms: “Chronic Bullous Disease of Chidhood”, “Linear Immunoglobulin A Bullous Disease”, “autoimmune bullous disease”, we carried out a review of the literature, using Google Scholar, PubMed and book in last 10 years. <strong>Conclusion : </strong>CBDC is a chronic bullous disease that appears in pediatric age. The pathogenesis of this disease is not yet known with certainty. Although the disease is capable of self-healing, dapsone is the recommended first-line treatment. If spontaneous recovery takes place, the prognosis is often optimistic. Accurate diagnosis and therapy are important for a prognosis.</p> <p>Latar belakang : Salah satu penyakit autoimun bulosa yang muncul pada decade pertama kehidupan adalah Penyakit Linear Immunoglobulin A yang awalnya disebut Chronic Bullous Disease of Childhood, merupakan kelainan kulit yang jarang terjadi dan tidak bersifat keturunan ditandai dengan akumulasi linear IgA. Lesi muncul sebagai vesikel bening atau hemoragik (atau keduanya) atau bula yang muncul dari kulit normal, kadang-kadang disertai dengan dasar eritematosa atau urtikaria. Bula atau vesikel biasanya tegang, ukurannya bervariasi, dan sering berkembang menjadi plak anular atau polisiklik akibat bergabungnya lesi. CBDC merupakan penyakit yang dapat sembuh dengan sendirinya, dengan sebagian besar anak mengalami pemulihan dalam waktu dua tahun sejak gejala muncul, dalam beberapa kasus, penyakit ini berlanjut hingga masa pubertas, namun biasanya tidak separah gejala awal. Tujuan : Tinjauan pustaka ini bertujuan untuk memberikan pemahaman yang komprehensif tentang CBDC, termasuk patogenesis, diagnosis dan pendekatan terapi yang tepat untuk penyakit ini. Metode : Dalam penelitian ini, menggunakan istilah kunci: “Penyakit Bulosa Kronis pada Anak”, “Penyakit Bulosa Imunoglobulin A Linear”, “penyakit bulosa autoimun”, kami melakukan telaah pustaka, menggunakan Google Scholar, PubMed dan buku dalam 10 tahun terakhir. Kesimpulan: CBDC merupakan penyakit bulosa kronis yang muncul pada usia anak-anak. Patogenesis penyakit ini belum diketahui secara pasti. Meskipun penyakit ini mampu sembuh sendiri, dapson merupakan pengobatan lini pertama yang direkomendasikan. Jika terjadi pemulihan spontan, prognosisnya sering kali optimis. Diagnosis dan terapi yang akurat penting untuk prognosis.</p> Revinanda Venincia Pangaribuan, Cut Putri Hazlianda Copyright (c) 2025 Revinanda Venincia Pangaribuan, Cut Putri Hazlianda https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/18780 Thu, 27 Feb 2025 00:00:00 +0700 Efficacy of Nintedanib for Idiopathic Pulmonary Fibrosis and Its Safety for Breastfeeding and Pregnancy https://talenta.usu.ac.id/scripta/article/view/16475 <p>Background : An interstitial lung disease called pulmonary fibrosis can cause breathing difficulties by leaving scars in the lungs. IPF is the most prevalent kind of PF. A multiple tyrosine kinase inhibitor called nintedanib received approval for use in antifibrotic treatment. There are two dosage forms for nintedanib: 100 mg and 150 mg for oral use. Two times a day, 150 mg should be taken with food. The FVC decrease was effectively reduced with nintedanib. In INPULSIS-1, INPULSIS-2, and a data set , the yearly rate of FVC decrease was considerably reduced in nintedanib users than in placebo users. The mortality rate from respiratory causes was 3.8% for patient received nintedanib as opposed to 5.0% for patient received placebo. In this review, we mainly reviewed reports on efficacy of nintedanib for IPF and its safety for breastfeeding and pregnancy.</p> <p>Method : This review extracted the resources from PubMed using the boolean method [”Efficacy of nintedanib” OR "nintedanib efficacy”] AND "pulmonary fibrosis”. Compared to people who used placebo in the INPULSIS-1 and INPULSIS-2 trials, nintedanib recipients showed significantly decreased annual rates of FVC. Before beginning nintedanib and as needed throughout treatment, confirm your pregnancy status. Women should be informed that breastfeeding is not advised due to the possibility of harmful side effects in nursing babies from nintedanib.</p> <p>Conclusion, patients treated with nintedanib observed a decreased rate of Interstitial Lung Disease development compared to who treated with placebo and it's not recommended for pregnant and breastfeeding women.</p> <p style="font-weight: 400;">latarbelakang: Penyakit paru interstisial yang disebut fibrosis paru dapat menyebabkan kesulitan bernapas dengan meninggalkan bekas luka di paru-paru. Fibrosis paru idiopatik merupakan jenis fibrosis paru yang paling banyak. Nintedanib merupakan inhibitor tirosin kinase yang digunakan dalam pengobatan antifibrotic. Ada dua bentuk sediaan nintedanib untuk dikonsumsi secara oral : 100 mg dan 150 mg. Dosis 150 mg dikonsumsi dua kali sehari bersama dengan makanan. Penggunaan nintedanib sangat efektif dalam penurunan <em>Forced Vital Capacity</em>(FVC) dalam INPULSIS-1, INPULSIS-2, dan kumpulan data, tingkat penurunan <em>Forced Vital Capatcity</em>(FVC) tahunan sangat berkurang pada pengguna nintedanib daripada pengguna plasebo. Tingkat kematian akibat penyebab pernapasan adalah 3,8% untuk pasien yang menerima nintedanib dibandingkan dengan 5,0% untuk pasien yang menerima plasebo. Dalam ulasan ini, kami meninjau laporan tentang kemanjuran nintedanib untuk fibrosis paru idiopatik dan keamanannya untuk menyusui dan kehamilan. <span style="font-weight: 400;">Metode: Ulasan ini mengambil sumber dari PubMed menggunakan metode boolean ["Efikasi nintedanib" ATAU "kemanjuran nintedanib"] DAN "fibrosis paru". Dibandingkan dengan orang yang menggunakan plasebo dalam uji coba INPULSIS-1 dan INPULSIS-2, penerima nintedanib menunjukkan tingkat <em>Forced Vital Capacity</em> (FVC) tahunan yang menurun secara signifikan. Sebelum memulai nintedanib dan sesuai kebutuhan selama perawatan, konfirmasikan status kehamilan Anda. </span></p> Resyana Santoso, Yoki Citra Perwira, Stevia Ariella Pasande Copyright (c) 2025 Resyana Santoso, Yoki Citra Perwira, Stevia Ariella Pasande https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/16475 Thu, 27 Feb 2025 00:00:00 +0700 The Relationship between Skin Diseases and Nutritional Deficiencies in Children https://talenta.usu.ac.id/scripta/article/view/18991 <p><strong>Background:</strong> Nutritional deficiencies are a significant global health issue, particularly in children, as they can impair growth and development. The skin often reflects early signs of nutritional deficiencies, including macronutrient and micronutrient imbalances, which may manifest as specific dermatological symptoms. Early identification of these manifestations is crucial to prevent long-term morbidity and mortality.</p> <p><strong>Aims:</strong> This review aims to explore the relationship between nutritional deficiencies and skin diseases in children, emphasizing clinical features, diagnostic approaches, and effective treatment strategies.</p> <p><strong>Methods:</strong> A comprehensive literature review was conducted using relevant studies and case reports on pediatric dermatological manifestations caused by macronutrient and micronutrient deficiencies.</p> <p><strong>Discussion</strong><strong>:</strong> Nutritional deficiencies, including protein-energy malnutrition, essential fatty acid deficiency, and deficiencies of vitamins A, B-complex, C, and K, as well as zinc and copper, present with a wide range of skin manifestations. These include xerosis, dermatitis, hyperkeratosis, hyperpigmentation, and petechiae. Diagnosis involves a combination of dietary history, clinical examination, and laboratory tests to assess nutritional status. Treatment requires nutritional supplementation tailored to the specific deficiency, alongside supportive dermatological care.</p> <p><strong>Conclusion:</strong> Dermatological manifestations are often the first indicators of nutritional deficiencies in children. Early recognition and a multidisciplinary approach to diagnosis and treatment are essential to improve outcomes. Future research should focus on integrating nutritional interventions with dermatological care to enhance recovery and prevent recurrence.</p> <div> <p><strong><span lang="ZH-CN">Latar Belakang:</span></strong><span lang="ZH-CN"> Defisiensi nutrisi merupakan masalah kesehatan global yang signifikan, terutama pada anak-anak, karena dapat mengganggu pertumbuhan dan perkembangan. Kulit sering kali mencerminkan tanda-tanda awal defisiensi nutrisi, termasuk ketidakseimbangan makronutrien dan mikronutrien, yang dapat muncul sebagai gejala dermatologis spesifik. Identifikasi dini manifestasi ini sangat penting untuk mencegah morbiditas dan mortalitas jangka panjang.</span></p> </div> <div> <p><strong><span lang="ZH-CN">Tujuan:</span></strong><span lang="ZH-CN"> Tinjauan ini bertujuan untuk men</span><span lang="EN-US">getahui </span><span lang="ZH-CN">hubungan antara defisiensi nutrisi dan penyakit kulit pada anak-anak, dengan </span><span lang="EN-US">melihat gambaran </span><span lang="ZH-CN">klinis, pendekatan diagnostik, dan strategi pengobatan yang efektif.</span></p> </div> <div> <p><strong><span lang="ZH-CN">Metode:</span></strong><span lang="ZH-CN"> Tinjauan literatur komprehensif dilakukan menggunakan studi dan laporan kasus yang relevan mengenai manifestasi dermatologis pada anak akibat defisiensi makronutrien dan mikronutrien.</span></p> </div> <div> <p><strong><span lang="EN-US">Diskusi</span></strong><strong><span lang="ZH-CN">:</span></strong><span lang="ZH-CN"> Defisiensi nutrisi, termasuk malnutrisi energi-protein, defisiensi asam lemak esensial, serta defisiensi vitamin A, B-kompleks, C, dan K, serta zinc dan tembaga, menunjukkan berbagai manifestasi kulit seperti xerosis, dermatitis, hiperkeratosis, hiperpigmentasi, dan petechiae. Diagnosis melibatkan kombinasi riwayat diet, pemeriksaan klinis, dan tes laboratorium untuk menilai status nutrisi. Pengobatan memerlukan suplementasi nutrisi yang disesuaikan dengan defisiensi spesifik, disertai perawatan dermatologis suportif.</span></p> </div> <div> <p><strong><span lang="ZH-CN">Kesimpulan:</span></strong><span lang="ZH-CN"> Manifestasi dermatologis sering kali menjadi indikator pertama defisiensi nutrisi pada anak-anak. Pengakuan dini dan pendekatan multidisiplin untuk diagnosis dan pengobatan sangat penting untuk meningkatkan hasil. Penelitian di masa depan perlu berfokus pada integrasi intervensi nutrisi dengan perawatan dermatologis untuk meningkatkan pemulihan dan mencegah kekambuhan.</span></p> </div> <p> </p> Nova Zairina Lubis, Fitriend Syahputri Copyright (c) 2025 Nova Zairina Lubis, Fitriend Syahputri https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/18991 Thu, 27 Feb 2025 00:00:00 +0700 Exclusive Breastfeeding Versus Combination Feeding on Incidence of Atopic Dermatitis: A Comparative Study https://talenta.usu.ac.id/scripta/article/view/17865 <p><strong>Background. </strong>In spite of the extensive research on the potential protective effects of exclusive breastfeeding in preventing the occurrence of atopic dermatitis and the involvement of cow’s milk allergy as a triggering factor, controversies regarding this issue persist. <strong>Objective</strong>. This study analyzes the comparison of the incidence of AD among infants exclusively breastfed compared to those who receive a combination of formula milk and breastfeeding. <strong>Methods</strong>. This study is an analytical research with a cross-sectional approach, conducted at Puskesmas Sentosa Baru Medan in August 2023. The sample consisted of 114 infants, which divided into two groups: exclusively breastfed infants and the other consisting of infants who received a combination of breastfeeding and formula milk, selected through consecutive sampling. The diagnosis of AD was based on a questionnaire modified from the Hanifin-Rajka criteria. <strong>Results</strong>. According to the research findings, among the exclusively breastfed infants, 11 (19,3%) were found to have AD, whereas in the opposing group, there were 12 (21,1%) cases of AD. Statistical analysis indicated no significant difference in the incidence of AD based on early feeding history (p=0,815). The prevalence ratio of AD infants from both study group is 1,10. <strong>Conclusions</strong>. Infants who receive a combination of breast milk and formula feeding have an elevated risk of 1,1 times for the onset of AD compared to those who are exclusively breastfed. There is no significant difference in the incidence of AD among infants who are exclusively breastfed and those who receive a combination of breast and formula feeding.</p> <p> </p> <p style="font-weight: 400;"><strong>Latar belakang.</strong> Meskipun telah banyak penelitian mengenai potensi efek perlindungan ASI eksklusif dalam mencegah terjadinya dermatitis atopik dan keterlibatan alergi susu sapi sebagai faktor pemicu, kontroversi mengenai hal ini masih terus berlanjut. <strong>Tujuan</strong>. Penelitian ini bertujuan untuk menganalisis perbandingan kejadian DA pada bayi yang mendapat ASI eksklusif dibandingkan dengan bayi yang mendapat kombinasi susu formula dan ASI. <strong>Metode</strong>. Penelitian ini merupakan penelitian analitik dengan pendekatan potong lintang, yang dilakukan di Puskesmas Sentosa Baru Medan pada bulan Agustus 2023. Sampel terdiri dari 114 bayi, yang dibagi menjadi dua kelompok yaitu bayi yang diberi ASI eksklusif dan bayi yang diberi kombinasi ASI dan susu formula, yang dipilih secara <em>consecutive sampling</em>. Selanjutnya, diagnosis DA didasarkan pada kuesioner yang dimodifikasi dari kriteria Hanifin-Rajka. <strong>Hasil</strong>. Menurut temuan penelitian, di antara bayi yang disusui secara eksklusif, 11 (19,3%) ditemukan menderita DA, sedangkan pada kelompok yang tidak disusui, terdapat 12 (21,1%) kasus DA. Analisis statistik menunjukkan tidak ada perbedaan yang signifikan dalam kejadian PJB berdasarkan riwayat pemberian makanan awal (p=0,815). Rasio prevalensi bayi AD dari kedua kelompok penelitian adalah 1,10. <strong>Kesimpulan</strong>. Bayi yang menerima kombinasi ASI dan susu formula memiliki risiko 1,1 kali lebih tinggi untuk mengalami PJB dibandingkan dengan bayi yang mendapat ASI eksklusif. Tidak ada perbedaan yang signifikan dalam kejadian DA antara bayi yang diberi ASI eksklusif dan mereka yang menerima kombinasi ASI dan susu formula.</p> Nova Zairina Lubis, Albert Wijaya, Hilfan Ade Putra Lubis, Muhammad Aron Pase Copyright (c) 2025 Nova Zairina Lubis, Albert Wijaya, Hilfan Ade Putra Lubis, Muhammad Aron Pase https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/17865 Thu, 27 Feb 2025 00:00:00 +0700 Fish Bone Analisis Respon Kesiapan Sistem Kesehatan di Indonesia Terhadap Pnyakit Pandemi: Sumber Daya Manusia, Keuangan, Pemerintah, dan Informasi https://talenta.usu.ac.id/scripta/article/view/19040 <p><strong>Background: </strong><span style="font-weight: 400;">Infectious diseases remain a major challenge for public health systems worldwide, with pandemics posing a significant threat capable of disrupting society, the economy, and healthcare systems. The Covid-19 pandemic in 2019 highlighted the importance of preparedness and response capabilities within the healthcare system to effectively mitigate the impact of crises. Indonesia faces unique challenges in its efforts to combat the pandemic, making it crucial to understand the readiness of Indonesia's healthcare system in addressing the pandemic for policy decision-making, resource allocation, and strategic planning aimed at strengthening public health resilience. </span><strong>Objective.</strong><span style="font-weight: 400;"> To understand the readiness response of the health system in Indonesia to pandemic diseases. </span><strong>Method.</strong><span style="font-weight: 400;"> Systematic review with a literature research type. The collection of research journals using secondary data obtained from previous research results. This was done by searching for relevant articles, as well as analyzing and synthesizing the relevant articles found through electronic databases such as Google Scholar and PubMed using keywords. </span><strong>Results.</strong><span style="font-weight: 400;"> A total of 10 articles were analyzed, and it was found that there were several shortcomings in various aspects during the pandemic, especially in the early stages, such as knowledge, facilities, availability of healthcare personnel, and community conditions. During the pandemic, many health responses were carried out by the health system in Indonesia. Indonesia's readiness actions in enforcing diagnosis and mass screening at the beginning of the Covid-19 pandemic were still less effective. </span><strong>Conclusion.</strong><span style="font-weight: 400;"> Indonesia's readiness for pandemic diseases still has several strengths and weaknesses, and to improve all policies during the pandemic, especially in the health sector, support from all components of the state is needed.</span></p> <p><strong>Keyword:<span style="font-weight: 400;"> Covid-19, Fish bone analysis, Indonesian Health System</span></strong></p> <p><strong>Latar belakang. </strong>Penyakit menular masih merupakan tantangan besar bagi sistem kesehatan masyarakat di seluruh dunia, dengan pandemi merupakan ancaman yang sangat besar, mampu mengganggu masyarakat, perekonomian, serta sistem layanan kesehatan. Pandemi Covid-19 pada tahun 2019 menyoroti pentingnya kesiapsiagaan dan kemampuan respon dalam sistem layanan kesehatan untuk memitigasi dampak krisis secara efektif. Indonesia menghadapi tantangan unik dalam upayanya memerangi paandemi sehingga memahami kesiapan sistem layanan kesehatan Indonesia dalam mengatasi pandemi sangat penting dalam pengambilan keputusan kebijakan, alokasi sumber daya, dan perencanaan strategis yang bertujuan untuk memperkuat ketahanan kesehatan masyarakat. <strong>Tujuan. </strong>Mengetahui respon kesiapan sistem kesehatan di Indonesia terhadap penyakit pandemi. <strong>Metode</strong>. Telaah sistematis dengan jenis penelitian kepustakaan. Pengumpulan jurnal-jurnal penelitian menggunakan data sekunder diperoleh dari hasil penelitian sebelumnya. ini dilakukan dengan pencarian artikel yang relevan, serta analisis dan sintesis artikel yang relevan yang dicari melalui database elektronik yaitu Google Scholar dan pubmed dengan menggunakan kata kunci. <strong>Hasil. </strong>Sebanyak 10 artikel dianalisis dan didapatkan hasil bahwa terdapat beberapa kekurangan dari berbagai aspek pada masa pandemi terutama di masa awal seperti pengetahuan, fasilitas, ketersediaan tenaga kesehatan dan kondisi masyarakat. Saat pandemi, banyak respon kesehatan yang telah dilakukan oleh sistem kesehatan di Indonesia. Tindakan kesiapan Indonesia dalam penegakan diagnosis dan skrining di masal di awal masa pandemi Covid-19 masih kurang efektif. <strong>Kesimpulan. </strong>Kesiapan negara Indonesia terhadap penyakit pandemi masih memiliki beberapa kelebihan dan kekurangan, dan untuk meningkatkan seluruh kebijakan dimasa pandemi terutama pada bidang kesehatan diperlukannya dukungan oleh seluruh komponen negara.</p> <p><strong>Keyword:</strong><span style="font-weight: 400;"> Covid-19, Fish bone analysis, Sistem Kesehatan Indonesia</span></p> Nisa Amira Ibrahim, Fauzan Azmi Hasti Habibi Samosir, Delia Tri Putri, Alyfia Sizqi Sekarfitri, Ahmad Iqmal Reezal, Monica Dwi Putri Copyright (c) 2025 Nisa Amira Ibrahim, Fauzan Azmi Hasti Habibi Samosir, Delia Tri Putri, Alyfia Sizqi Sekarfitri, Ahmad Iqmal Reezal, Monica Dwi Putri https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/19040 Thu, 27 Feb 2025 00:00:00 +0700 Hubungan Tingkat Pengetahuan Pasien Wanita di Rumah Sakit Haji Adam Malik Medan Tentang Kanker Leher Rahim Dengan Pelaksanaan Deteksi Dini Kanker Leher Rahim https://talenta.usu.ac.id/scripta/article/view/18389 <p style="font-weight: 400;"><strong><em>Introduction</em></strong><em>.</em><em>Cervical cancer is a cancer of the lower uterus caused by infection with Human Papilloma Virus (HPV). Various factors in women can influence the incidence of cervical cancer, including sexually transmitted diseases, coitus and separation at young age, multiple partners, parity, and using of oral contraceptive pills</em><em>. Through prevention measures and early illness identification, the government is attempting to lower the prevalence of cervical cancer</em><em>. It is important to know the level of knowledge and factors that influence the implementation of early detection because they can affect to carrying out early detection screening. </em><strong><em>Objectives</em></strong><em>.</em> <em>T</em><em>o see the relationship between the level of knowledge of married female patients at HAM General Hospital and the implementation of early detection of cervical cancer.</em> <strong><em>Method</em></strong><em>.</em><em> The research used an analytic survey study with cross-sectional design will be conducted using questionnaire data with sample of 62 married female patients using a consecutive sampling technique. The analysis using the SPSS program in univariate and bivariate ways with 90% confidence level.</em> <strong><em>Result</em></strong><em>.</em><em> From 62 samples, the results obtained were the level of knowledge of respondents in "good/enough" category who had detected 10 people (16.1%) and who never had 36 people (58.1%). 16 people (25.8%) in the “less” category have never received early detection.</em> <strong><em>Conclusion</em></strong> <em>There is a significant relationship was found between the level of knowledge of married female patients and the implementation of early detection of cervical cancer. </em></p> <p><strong>Pendahuluan</strong>.Kanker leher rahim merupakan kanker yang berada di bagian bawah rahim yang disebabkan oleh infeksi Human Papilloma Virus (HPV). Berbagai faktor pada wanita dapat memengaruhi kejadian kanker leher rahim diantaranya penyakit menular seksual, koitus di usia muda, apartus di usia muda, berganti-ganti pasangan, paritas, penggunaan pil kontrasepsi oral. Upaya pemerintah untuk menekan angka kejadian kanker leher rahim salah satunya dengan program pencegahan melalui deteksi dini kanker leher rahim. Tingkat pengetahuan dan faktor-faktor yang memengaruhi pelaksanaan deteksi dini penting untuk diketahui karena dapat memengaruhi dalam kepatuhan melaksanakan skrining deteksi dini. <strong>Tujuan</strong>. Untuk melihat hubungan antara tingkat pengetahuan pasien wanita yang telah menikah di RSUP HAM Medan dengan pelaksanaan deteksi dini kanker leher rahim. <strong>Metode. </strong>Penelitian dengan jenis survey analitik dengan metode cross sectional ini akan dilakukan menggunakan data kuesioner dengan jumlah sampel 62 pasien wanita yang telah menikah dengan teknik pengambilan consecutive sampling. Analisis dilakukan menggunakan program SPSS secara univariat dan bivariat dengan tingkat kepercayaan 90%. <strong>Hasil</strong>. Dari 62 sampel, diperoleh hasil tingkat pengetahuan responden kategori baik/cukup yang pernah melakukan deteksi dengan jumlah 10 orang (16.1 %), dan yang tidak pernah dengan jumlah 36 orang (58.1 %). Kategori kurang secara keseluruhan tidak pernah melakukan deteksi dini sejumlah 16 orang (25.8 %). <strong>Kesimpulan.</strong> Ditemukan hubungan yang signifikan antara tingkat pengetahuan pasien wanita yang telah menikah dengan pelaksanaan deteksi dini terhadap kanker leher rahim.</p> <p> </p> <p> </p> Shafira Utami, Yudha Sudewo, Khairani Sukatendel, Fauzan Azmi Hasti Habibi Samosir, Rizky Adriansyah Copyright (c) 2025 Shafira Utami, Yudha Sudewo, Khairani Sukatendel, Fauzan Azmi Hasti Habibi Samosir, Rizky Adriansyah https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/18389 Thu, 27 Feb 2025 00:00:00 +0700 Risk Factors of Acute Coronary Syndrome in Adam Malik General Hospital https://talenta.usu.ac.id/scripta/article/view/19293 <p><strong>Background :</strong> Coronary Artery Disease (CAD) has been nominated as the world’s biggest killer due to its participation in 16% of mortality cases globally. Unstable Angina Pectoris (UAP), Non ST-Elevation Myocardial Infarction (NSTEMI), and ST-Elevation Myocardial Infarction (STEMI) are parts of CAD that united into a term called Acute Coronary Syndrome (ACS). Several risk factors have been linked to ACS phenomenon and categorized into modifiable and in-modifiable risk factors. <strong>Objective : </strong>This study aims to discover the existing risk factors in ACS patients at Adam Malik General Hospital within 2022-2023 period. <strong>Method : </strong> This study is a descriptive with cross-sectional design and retropective approach. The data is a secondary data from medical record that fullfils the criteria. <strong>Result : </strong>Among the 190 patients, 170 patients (89,5%) were &gt;45 years old, 114 patients (75,8%) were male, 104 patients (54,7%) were smokers, 118 patients (62,1%) had hypertension, 71 patients (37,4%) had diabetes, 65 patients (34,2%) were obese, and 114 patients (60%) had dyslipidemia. <strong>Conclusion : </strong>The unmodifiable risk factors in this study were age and gender, whilst the modifiable risk factors were smokers, hypertension, diabetes, obese, and dyslipidemia. The most frequent risk factor was hypertension which was found in 60% of the patients</p> <p style="font-weight: 400;"><strong><em>Latar belakang</em></strong><em> : Penyakit Jantung Koroner (PJK) dimobatkan sebagai penyebab kematian terbesar di dunia akibat perannya pada 16% kasus kematian secara global. Angina Pektoris Tidak Stabil (APTS), Non-ST levation Myocardial Infarction (NSTEMI), dan ST-Elevation Myocardial Infarction (STEMI) adalah bagian dari PJK yang disatukan dalam Sindroma Koroner Akut (SKA). Beberapa faktor risiko telah dihubungkan dengan kejadian SKA dan dikategorikan menjadi faktor risiko yang tidak dapat dimodifikasi dan faktor risiko yang dapat dimodifikasi. <strong>Tujuan</strong> : Penelitian ini bertujuan untuk menelusuri faktor risiko yang terjadi pada pasien SKA di RSUP Haji Adam Malik pada periode 2022-2023. Data yang digunakan adalah data sekunder dari rekam medik yang memenuhi kriteria. <strong>Hasil</strong> : Dari 190 pasien, 170 pasien (89,5%) berusia &gt;45 tahun, 114 pasien (75,8%) adalah laki-laki, 104 pasien (54,7%) adalah perokok, 118 pasien (62,1%) penderita hipertensi, 71 pasien (37,4%) penderita diabetes, 65 pasien (34,2%) obesitas, 114 pasien (60%) penderita dislipidemia. <strong>Kesimpulan </strong>: Faktor risiko yang tidak dapat dimodifikasi pada penelitian ini adalah usia dan jenis kelamin, sementara faktor risiko yang dapat dimodifikasi adalah perokok, hipertensi, diabetes, obesitas, dan dislipidemia. Faktor risiko yang paling banyak terjadi adalah hipertensi yang didapatkan pada 60% pasien</em></p> Jessi Vania Tambarta, Cut Aryfa Andra , Lili Rohmawati , Aryani Atiyatul Amra Copyright (c) 2025 Jessi Vania Tambarta, Cut Aryfa Andra , Lili Rohmawati , Aryani Atiyatul Amra https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/19293 Thu, 27 Feb 2025 00:00:00 +0700 The Relationship between Gadgets Use and Sleep Quality of Medical Education Students at the Faculty of Medicine, Syiah Kuala University in 2023 https://talenta.usu.ac.id/scripta/article/view/18602 <p><strong><span class="s8">Background:</span></strong><span class="s9">The use of gadgets has a big impact in making everyday communication easier. Sleep quality is a measure of how easy it is for a person to start sleeping and maintain sleep. The quality of a person's sleep can be described by the length of time they sleep and complaints or after waking up</span><strong><span class="s9">. </span><span class="s8">Objectives:</span></strong><span class="s9">This study aims to determine the relationship between the use of devices and sleep quality among medical </span><span class="s9">students</span><span class="s9"> class of 2021, Faculty of Medicine, Syiah Kuala University. </span><strong><span class="s8">Methods: </span></strong><span class="s9">This research uses quantitative methods with a </span><span class="s9">cross sectional</span><span class="s9"> approach. The sampling technique used is cluster sampling. The analysis techniques used are univariate tests and bivariate tests. The data used is primary data and secondary data. The number of samples in this study was 199 respondents</span><strong><span class="s9">. </span><span class="s8">Results:</span></strong><span class="s9">The results of the research show that 11.6% of medical students at the class of 2021 medical school at Syiah Kuala University are in the normal category and 88.4% are not normal. Meanwhile, 53.8% of the sleep quality was in the good category and 46.2% was poor. </span><strong><span class="s8">Conclusion:</span></strong><span class="s9">This research shows that there is a relationship between the use of devices on sleep quality and value (</span><span class="s9">p</span><span class="s9">= 0.002).</span><strong><br />Latar Belakang: </strong>Penggunaan gawai memiliki dampak besar dalam mempermudah komunikasi sehari-hari. Kualitas tidur adalah ukuran dimana seseorang itu dapat kemudahan dalam memulai tidur dan untuk mempertahankan tidur, kualitas tidur seseorang dapat digambarkan dengan lama waktu tidur dan keluhan-keluhan ataupun sehabis bangun tidur. <strong>Objektif: </strong>Penelitian ini bertujuan mengetahui gambaran hubungan antara penggunaan gawai terhadap kualitas tidur pada mahasiswa pendidikan dokter angkatan 2021 fakultas kedokteran universitas syiah kuala.<strong> Metode:</strong> Penelitian ini menggunakan metode kuantitatif dengan pendekatan cross sectional. Teknik pengambilan sampel yang digunakan adalah <em>cluster sampling</em>. Teknik analisis yang digunakan yaitu uji univariat dan uji bivariat. Untuk data yang digunakan adalah data primer dan data sekunder. Jumlah sampel pada penelitian ini sebanyak 199 responden. <strong>Hasil: </strong>Hasil penelitian menunjukkan penggunaan gawai pada mahasiswa Pendidikan dokter Angkatan 2021 fakultas kedokteran Universitas Syiah Kuala sebanyak 11,6% termasuk kategori normal dan 88,4% tidak normal. Sedangkan kualitas tidurnya sebanyak 53,8% termasuk kategori baik dan 46,2% kurang baik. <strong>Kesimpulan: </strong>Pada penelitian ini menunjukkan adanya hubungan antara penggunaan gawai terhadap kualitas tidur dengan nilai (p = 0,002).</p> muhammad lana ovanda, Tilaili Ibrahim, Sakdiah, Muhammad Yani, Rovy Pratama Copyright (c) 2025 muhammad lana ovanda, Tilaili Ibrahim, Sakdiah, Muhammad Yani, Rovy Pratama https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/18602 Thu, 27 Feb 2025 00:00:00 +0700 The Relationship Between Sufficient Knowledge and Behavior of Medical Students in Faculty of Medicine Universitas Sumatera Utara regarding Acne Vulgaris https://talenta.usu.ac.id/scripta/article/view/14600 <p style="font-weight: 400;"><strong>ABSTRACT</strong></p> <p style="font-weight: 400;">Acne vulgaris is a chronic inflammation of pilosebaceous follicles caused by <em>Propionibacterium acnes</em>. The clinical symptoms are polymorphic skin eruption, especially blackheads, non-inflammatory papule, pustule, nodule, and cyst formation. Generally, patients tend to complain of the aesthetic disfigurement caused by acne vulgaris. Even though it is not life-threatening, acne vulgaris can seriously harm patients’ confidence and might cause depression. One of risk factors is lack of knowledge and bad behavior. This research aimed to study the knowledge and behavior of medical students in University of North Sumatra regarding acne vulgaris in 2018. The research was observational cross-sectional study. Eighty-eight medical students in University of North Sumatra that fulfilled the inclusion criteria in this study were recruited and were randomized using consecutive sampling. The data was obtained by filling in the questionnaire to evaluate their knowledge and behavior. The accumulated data were processed with computer. The level of knowledge of the medical students in University of North Sumatra is 43.2% (sufficient) and the behavior of the medical students in University of North Sumatra was 68.2% (sufficient). There was a significant relationship between knowledge and behavior of the medical students in University of North Sumatera and acne vulgaris.</p> <p style="font-weight: 400;"><strong>Keywords: Acne Vulgaris, Behavior, Knowledge, University Student</strong></p> <p style="font-weight: 400;"><strong> </strong></p> <p style="font-weight: 400;"><strong><em>ABSTRAK</em></strong></p> <p style="font-weight: 400;"><em>Acne vulgaris merupakan inflamasi kronis folikel pilosebasea yang disebabkan oleh Propionibacterium acne. Gejala klinis yang muncul umumnya berupa erupsi kulit polimorfik dengan dominasi komedo hitam, papula non-inflamasi, pustula, nodus, dan kista. Secara umum, pasien sering mengeluhkan gangguan kosmetik yang ditimbulkan akibat acne vulgaris. Walaupun tidak mengancam jiwa, acne vulgaris dapat membahayakan pasien karena dapat menyebabkan krisis kepercayaan dan depresi. Salah satu faktor risiko adalah pengetahuan dan perilaku buruk. Penelitian ini bertujuan untuk menilai pengetahuan dan sikap mahasiswa kedokteran di Universitas Sumatera Utara (USU) tentang acne vulgaris pada 2018. Penelitian ini berupa penelitian observasional potong-lintang. Sampel penelitian adalah 88 mahasiswa kedokteran USU yang memenuhi kriteria</em><em> inklusi yang kemudian diacak menggunakan metode consecutive sampling. Data berasal dari kuesioner yang maharsiswa dengan acne vulgaris untuk menilai pengetahuan dan sikap yang selanjutnya diolah menggunakan komputer. Pengetahuan sampel didapati 43,2% (cukup), sedangkan sikap 68,2% (cukup). Penelitian berkesimpulan terdapat hubungan signifikan antara pengetahuan dan sikap mahasiswa kedokteran USU terkait acne vulgaris.</em></p> <p style="font-weight: 400;"><strong><em>Kata Kunci: Acne vulgaris, mahasiswa kedokteran, pengetahuan, sikap </em></strong></p> Josapat Bima Sakti Sitepu, Cut Putri Hazlianda Copyright (c) 2025 Cut Putri Hazlianda, Josapat https://creativecommons.org/licenses/by-nc/4.0 https://talenta.usu.ac.id/scripta/article/view/14600 Thu, 27 Feb 2025 00:00:00 +0700