Teratogenic Effects of Arabica Coffee (Coffea arabica L) on Rats During the Organogenesis Period
DOI:
https://doi.org/10.32734/idjpcr.v3i2.4311Abstract
The purpose of the research was to evaluate the teratogenic effect caused by the
provision of Arabica coffee solution with variations of 0.36 ml, 0.72 ml and 1.08 ml with
positive control of caffeine at a dose of 300 mg / kg bw to rats during organogenesis. The
measurement parameters in this study are the appearance of reproduction, external
malformations and scalal malformations. The results in this study found that the
administration of Arabica coffee solution with a volume of 1.08 ml and caffeine 300 mg /
kg bb caused an abnormality in the reproductive appearance of weight loss and body length,
whereas for extrenal malformation and scalal malforation no abnormalities were found in
each administration of the solution Arabica coffee and caffeine.
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