Equianalgesic Oxycodone, Continuous Intravenous Morphine in Post- Long Bone Surgery

Authors

  • Franz Josef Tarigan Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sumatera Utara
  • Achsanuddin Hanafie Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sumatera Utara
  • Hasanul Arifin Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sumatera Utara
  • Dadik Wahyu Wijaya Anesthesiologist & Intensivist. RSUP H Adam Malik

DOI:

https://doi.org/10.32734/sumej.v2i3.1240

Keywords:

Oxycodone, Morphine, Opiates, Visual Analogue Score, Equianalgesic Dose

Abstract

Oxycodone and morphine are powerful analgesic drugs used for post-operative pain management. There is no studies have been conducted to assess the dose equivalency between the two drugs. To get an equianalgesic dose of Oxycodone and Morphine. This study was using a double-blind randomized clinical trials, 48 samples, ages 21-60 years, PS ASA I-II, which will get an elective orthopedic surgery using general anesthesia tech-niques. Oxycodone (group A) : Morphine (group B) (Initial 5mg than continuous 1 mg/hour : initial dose 4mg than continuous 0,5 mg/hour). Average drug dose for group that takes morphine and oxycodone  (3.90 ± 0.46 mg : 1.46 ± 0.51 mg).  No significant difference between the average dose (p <0.05).  Equianalgesic dosein group Oxycodone and Morphine is 1.4 mg: 3.9mg.

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References

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Published

2019-09-30

How to Cite

1.
Franz Josef Tarigan, Hanafie A, Arifin H, Wijaya DW. Equianalgesic Oxycodone, Continuous Intravenous Morphine in Post- Long Bone Surgery . Sumat. Med. J. [Internet]. 2019Sep.30 [cited 2024Nov.24];2(3):133-45. Available from: https://talenta.usu.ac.id/smj/article/view/1240

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