SYNTAX Score II as a Predictor of One-Year Major Adverse Cardiovascular Events in Patients with Chronic Coronary Syndrome and Type 2 Diabetes Mellitus Undergoing Percutaneous Coronary Intervention

Authors

  • Elsa Tamara Saragih Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20155, Indonesia
  • Harris Hasan Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20155, Indonesia
  • Abdul Halim Raynaldo Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20155, Indonesia
  • Cut Aryfa Andra Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20155, Indonesia
  • Teuku Bob Haykal Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20155, Indonesia
  • Kamal Kharazzi Ilyas Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20155, Indonesia

DOI:

https://doi.org/10.32734/sumej.v9i2.23616

Keywords:

chronic coronary syndrome, major adverse cardiovascular events, syntax II, type 2 diabetes mellitus

Abstract

Background: The severity of coronary atherosclerotic lesions is an important determinant of cardiovascular events in patients with CAD. The SS-II (SYNTAX-II) score, which integrates anatomical characteristics with clinical variables, provides improved prognostic value compared with anatomical scoring alone. Objective: To determine whether the SS-II predicts one-year MACE in CCS patients with T2DM who undergo PCI. Methods: This observational analytic study employed a retrospective cohort design including patients treated from June 2023 to August 2024. A total of 128 CCS patients with T2DM who underwent PCI were enrolled. Bivariate and multivariate analyses were performed to examine the association between the SS-II and MACE. One-year MACE-free survival was analyzed using Kaplan–Meier curves.  Results: MACE occurred more frequently among patients with high SS-II scores (22 [34.4%], P < 0.001). Mortality and acute heart failure were both significantly associated with the SS-II (P = 0.042 and P = 0.03, respectively). Patients with high scores had significantly lower one-year MACE-free survival. Conclusion: The SS-II is a valuable predictor of one-year MACE in CCS patients with T2DM undergoing PCI.

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References

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Published

2026-05-01

How to Cite

1.
Elsa Tamara Saragih, Hasan H, Raynaldo AH, Andra CA, Haykal TB, Ilyas KK. SYNTAX Score II as a Predictor of One-Year Major Adverse Cardiovascular Events in Patients with Chronic Coronary Syndrome and Type 2 Diabetes Mellitus Undergoing Percutaneous Coronary Intervention. Sumat. Med. J. [Internet]. 2026 May 1 [cited 2026 May 1];9(2):92-9. Available from: https://talenta.usu.ac.id/smj/article/view/23616

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