The Tooth Agenesis in Clinical Practice: A review of Case Reports

Authors

  • Michael Dany Faculty of Dentistry, Universitas Sumatera Utara
  • Ameta Primasari Faculty of Dentistry, Universitas Sumatera Utara
  • Ervina Sofyanti Faculty of Dentistry, Universitas Sumatera Utara
  • Sry Suryani Widjaja Faculty of Medicine, Universitas Sumatera Utara
  • Thantrira Porntaveetus Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand

DOI:

https://doi.org/10.32734/dentika.v28i1.20149

Keywords:

Prevalence, Tooth Agenesis, Non-syndromic

Abstract

Tooth agenesis (TA) relates to multiple congenital dental disorder and the most prevalent developmental disorders affecting approximately 200 million people globally. The management of TA require interdisciplinary dental approaches. Therefore, this study aimed to conduct a case report evaluation of TA based on population and ethnicity. This scoping reviews based on  Preferred Reporting Items for Systematic Reviews and Meta-Analyses, has been registered in Open Science Framework. Relevant articles were retrieved from Proquest, Science Direct, PubMed, and SpringerLink databases with keywords comprising of ‘Prevalence’ AND ‘Tooth Agenesis’ AND ‘Nonsyndromic or Syndromic’. From 2014 to 2024, there were only five non-syndromic tooth agenesis case reports were included to be reviewed. The review of multiple case reports of tooth agenesis demonstrated significant variability in clinical and radiography evaluation involving inheritance pattern. By early identification in mixed dentition, the comprehensive and individualized treatment approaches are required to address both esthetics and functional outcomes. Further population-based studies of genetic involvement in TA can contribute early detection of malocclusion.   

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Author Biographies

Ameta Primasari, Faculty of Dentistry, Universitas Sumatera Utara

Department of Oral Biology

Ervina Sofyanti, Faculty of Dentistry, Universitas Sumatera Utara

Department of Orthodontics

Sry Suryani Widjaja, Faculty of Medicine, Universitas Sumatera Utara

Department of Biochemistry

Thantrira Porntaveetus, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand

Center of Excellence in Genomics and Precision Dentistry, Department of Physiology

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Published

2025-07-30

How to Cite

Michael Dany, Ameta Primasari, Ervina Sofyanti, Sry Suryani Widjaja, & Thantrira Porntaveetus. (2025). The Tooth Agenesis in Clinical Practice: A review of Case Reports. Dentika: Dental Journal, 28(1), 84–97. https://doi.org/10.32734/dentika.v28i1.20149

Issue

Section

Literature Review

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