Formulasi Nanoemulsi Ekstrak Jahe (Zingiber officinale) Berbasis Minyak Bekatul dengan Penambahan Tween 80 dan PEG 400 sebagai Surfaktan-Kosurfaktan

Nisaul Fadilah Dalimunthe; Fitri Annisa; Rizkyka Tria Ramadhan; Valencia Vazelim; Michael Michael; Thiodorus Marvin Tjandra

doi:10.32734/jtk.v15i2.22503

Authors

Nisaul Fadilah Dalimunthe Universitas Sumatera Utara
Fitri Annisa Universitas Sumatera Utara
Rizkyka Tria Ramadhan Universitas Sumatera Utara
Valencia Vazelim Universitas Sumatera Utara
Michael Michael Universitas Sumatera Utara
Thiodorus Marvin Tjandra Universitas Sumatera Utara

DOI:

https://doi.org/10.32734/jtk.v15i2.22503

Keywords:

ginger extract, rice bran oil, cosurfactant, nanoemulsion

Abstract

Ginger extract (Zingiber officinale) contains bioactive compounds such as gingerol, shogaol, zingerone, and zingiberol, making it promising for nanoemulsion formulations that enhance solubility and bioavailability of natural active compounds. This study aimed to determine the optimal nanoemulsion formulation using rice bran oil as the independent variable, with Tween 80, PEG 400, and ginger extract as fixed variables across six formulations. Tween 80 acts as a surfactant reducing lipophilic globule size, while PEG 400 acts as a cosurfactant enhancing effectiveness through increased penetration. Nanoemulsions were prepared by mixing the four ingredients, then evaluated for organoleptic properties, pH, emulsion type, transmittance, and emulsification time. All formulas showed pH 6.52–6.72, an oil-in-water (O/W) type, and emulsification times <1 minute (grade A). The formulation with 2.5 mL rice bran oil, 12.5 mL Tween 80, and 15 mL PEG 400 gave the best result, with the highest transmittance and particle size of 25.58 nm.

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