Diabetic Ketoacidosis in Type 1 Diabetes Mellitus

Authors

  • Lukman Nurhakim Department of Internal Medicine, Faculty of Medicine, Universitas Andalas, Padang, 25163, Indonesia
  • Rudy Afriant Division of Medical Hemato-oncology, Department of Internal Medicine, Faculty of Medicine, Universitas Andalas, Padang, 25163, Indonesia
  • Dinda Aprilia Division of Medical Endocrine Metabolic, Department of Internal Medicine, Faculty of Medicine, Universitas Andalas, Padang, 25163, Indonesia

DOI:

https://doi.org/10.32734/sumej.v7i1.11837

Keywords:

diabetic ketoacidosis, diabetes mellitus type 1, insulin, hormones

Abstract

Background: Diabetic ketoacidosis (DKA) is a state of metabolic decompensation/disorder characterized by the triad of hyperglycemia, acidosis and ketosis, caused by absolute or relative insulin deficiency and increased counter-regulatory hormones. Objective: To report a case of diabetic ketoacidosis (DKA) in a young adult patient with type 1 diabetes mellitus and scalp abscess, emphasizing the importance of early diagnosis and prompt management to achieve clinical improvement. Methods: This case report describes the clinical presentation, diagnostic approach, and therapeutic management of a 19-year-old male with DKA. Results: A 19-year-old male treated in the internal medicine ward of Dr. M djamil Padang with diabetic ketoacidosis, type 1 DM, and Abscess capitis. The patient was treated with rehydration and intravenous insulin infusion can show clinical improvement. Conclusion: The diagnosis in patients is based on anamnesis, physical examination and supporting examinations. Immediate therapy is needed in the management of DKA in patients. After DKA is resolved, look for the causes of the risk of DKA. On the third day of treatment the patient's condition improved clinically and the laboratory.

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References

Tarigan TJ. Ketoasidosis diabetik. Dalam: Buku ajar Ilmu Penyakit Dalam. 6th ed. Jakarta: Pusat Penerbitan Ilmu Penyakit Dalam. 2014;2375–80.

American Diabetes Association. Hyperglycemic crisis in diabetes. Diabetes Care. 2019;27(1):94–102.

Hong JYH, Jalaludin MY, Mohamad AB, et al. Diabetic ketoacidosis at diagnosis of type 1 diabetes mellitus in Malaysian children and adolescents. Malaysian Physician. 2015;10(3):11–18.

Seth P, Kaur H, Kaur M. Clinical profile of diabetic ketoacidosis: a prospective study in a tertiary care hospital. J Clin Diagn Res. 2015;9:1–4.

Shaltout AA, Channanath AM, Thanaraj TA, et al. Ketoacidosis at first presentation of type 1 diabetes mellitus among children: a study from Kuwait. Sci Rep. 2016;6:27519.

Gosmanov RA, Gosmanova EO, Kitabchi EA. Hyperglicemic crises: diabetic ketoacidosis (DKA) and hiperglycemic hiperosmolar state (HHS). National Instituteof Health. 2018.

National Institute for Health and Care Excellence. Type 1 diabetes in adults: diagnosis and management. NICE guideline. 2022.

Kitabchi AE, Umpierrez GE, Miles JM, Fisher JN. Hyperglycemic crises in adult patients with diabetes. Diabetes Care. 2009;32(7):1335–43.

Dhatariya KK, Vellanki P. Treatment of diabetic ketoacidosis (DKA)/hyperglycemic hyperosmolar state (HHS): Novel advances in the management of hyperglycemic crises (UK versus USA). Curr Diab Rep. 2017;17(5):33.

Wolfsdorf JI, Glaser N, Agus M, Sperling MA, Hanas R, Codner E, et al. ISPAD Clinical Practice Consensus Guidelines 2018: Diabetic ketoacidosis and hyperglycemic hyperosmolar state. Pediatr Diabetes. 2018;19(Suppl 27):155-77.

Fayfman M, Pasquel FJ, Umpierrez GE. Management of hyperglycemic crises: diabetic ketoacidosis and hyperglycemic hyperosmolar state. Med Clin North Am. 2017;101(3):587-606.

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Published

2024-01-01

How to Cite

1.
Nurhakim L, Afriant R, Aprilia D. Diabetic Ketoacidosis in Type 1 Diabetes Mellitus. Sumat. Med. J. [Internet]. 2024Jan.1 [cited 2025May12];7(1):43-5. Available from: https://talenta.usu.ac.id/smj/article/view/11837