Obstructive Sleep Apnea in Patients with Heart Failure and Atrial Fibrillation

Authors

  • Anggia Chairuddin Lubis Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20154, Indonesia
  • Yuke Sarastri Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20154, Indonesia
  • Cut Aryfa Andra Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20154, Indonesia
  • Nadiah Masyab Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20154, Indonesia
  • Hana Fauziyah Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara and Adam Malik Hospital, Medan, 20154, Indonesia

DOI:

https://doi.org/10.32734/sumej.v8i3.16701

Keywords:

atrial fibrillation, heart failure, obstructive sleep apnea

Abstract

Background: Obstructive sleep apnea (OSA) is an independent risk factor for heart failure and atrial fibrillation. Therefore, effective detection and management of OSA are essential. Objective: The study aimed to determine how common obstructive sleep apnea is among patients with heart failure and atrial fibrillation. Methods: We performed a cross-sectional study assessing the prevalence of OSA in hospitalized patients with both conditions, following the latest European Society of Cardiology Guidelines for heart failure assessment and using polysomnography to evaluate OSA. Results: The study included 30 subjects; 22 (73.3%) were men, and 18 (60%) were over 60 years old. Polysomnography revealed that 23 (80.0%) had OSA, with 4 (23.5%) in the severe category and an average AHI of 18.3 ± 14.7. Among participants, 11 (65%) with ejection fraction ≤ 40%, 12 (40%) had obesity, 11 (36.7%) had Type 2 diabetes, 19 (63.6%) had hypertension, 20 (66.7%) had coronary artery disease, and 3 (10%) had a history of stroke. Most participants (60%) had a history of smoking. Conclusion: This study shows a high prevalence of OSA among patients with heart failure and atrial fibrillation, especially in men and those with reduced ejection fraction.

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References

Santos I, Rochal I, Gozal D. Obstructive Sleep Apnea, Shift Work and Cardiometabolic Risk. 2020;74:132–140.

André S, Dupuis G, Collet JP, et al. Cardiometabolic comorbidities in obstructive sleep apnea patients are related to disease severity, nocturnal hypoxemia, and decreased sleep quality. Respir Res. 2020;21(1):1–10. Available from: https://doi.org/10.1186/s12931-020-1284-7.

Gami AS, Hodge DO, Herges RM, et al. Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation. J Am Coll Cardiol. 2007;49(5):565–571. Available from: https://doi.org/10.1016/j.jacc.2006.08.060.

Carlisle, MA, Fudim, M, DeVore, AD, Piccini, J.P. Heart failure and atrial fibrillation, like fire and fury. JACC Heart Fail. 2019;7(6):447–456. Available from: https://doi.org/10.1016/j.jchf.2019.03.005.

Arzt M, Bradley TD. Treatment of sleep apnea in heart failure. Am J Respir Crit Care Med. 2006;173(12):1300–1308. Available from: https://doi.org/10.1164/rccm.200511-1745PP.

Delesie M, Simons SO, Bracke FA, et al. The value of screening questionnaires/scoring scales for obstructive sleep apnoea in patients with atrial fibrillation. Arch Cardiovasc Dis. 2021;114(11):737–747. Available from: https://doi.org/10.1016/j.acvd.2021.08.002.

Ardelean CL, Lighezan DF, Pescariu S, Nadasan V, Pleava R, Mihaicuta S. Sleep apnea syndrome and heart failure—mechanisms and consequences. Pneumologia. 2019;68(2):61–67. Available from: https://doi.org/10.2478/pneum-2019-0017.

McDonagh TA, Metra M, Adamo M, et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2021;42(36):3599–3726. Available from: https://doi.org/10.1093/eurheartj/ehab368.

Berry RB, Brooks R, Gamaldo CE, et al. The AASM Manual for the Scoring of Sleep and Associated Events. Version 2.4. Darien (IL): American Academy of Sleep Medicine; 2017.

Jensen MH, Nørgaard BL, Andersen M, et al. Prevalence of sleep apnea in unselected patients with atrial fibrillation by a home-monitoring device: The DAN-APNO study. IJC Heart Vasc. 2023;47:101219. Available from: https://doi.org/10.1016/j.ijcha.2023.101219.

Spicuzza L, Caruso D, Maria G. Obstructive sleep apnoea syndrome and its management. Ther Adv Chronic Dis. 2015;6(5):273–285. Available from: https://doi.org/10.1177/2040622315590318.

Mills EW, Antman EM, Javaheri S. Breathless nights and heart flutters: Understanding the relationship between obstructive sleep apnea and atrial fibrillation. Heart Rhythm. 2023;20(9):1267-73.

Hjälm HH, Thunström E, Glantz H, Karlsson M, Celik Y, Peker Y. Obstructive sleep apnea severity and prevalent atrial fibrillation in a sleep clinic cohort with versus without excessive daytime sleepiness. Sleep Med. 2023;112:63–69. Available from: https://doi.org/10.1016/j.sleep.2023.09.012.

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Published

2025-09-01

How to Cite

1.
Lubis AC, Yuke Sarastri, Cut Aryfa Andra, Nadiah Masyab, Hana Fauziyah. Obstructive Sleep Apnea in Patients with Heart Failure and Atrial Fibrillation. Sumat. Med. J. [Internet]. 2025Sep.1 [cited 2025Sep.6];8(3):158-61. Available from: https://talenta.usu.ac.id/smj/article/view/16701