Changes In Glutamic Oxaloacetic Transaminase Serum (SGOT) and Glutamic Pyruvic Transaminase Serum (SGPT) Value In Laparoscopic Cholecystectomy Patient at USU Hospital

Authors

  • Aziizah Gita Student
  • Adi Muradi Muhar 2Department of Digestive Surgery, Faculty of Medicne, Universitas Sumatera Utara

DOI:

https://doi.org/10.32734/sumej.v3i2.3273

Keywords:

Laparoscopic cholecystectomy, SGOT, SGPT, Wilcoxon

Abstract

Background. Laparoscopic cholecystectomy has become more widely used choice compared to laparotomy cholecystectomy. Laparoscopic cholecystectomy has now become the gold standard of abdominal surgery for abdominal surgery for gallbladder abnormalities, more than 90% of patients with gallstone disease are treated surgically by laparoscopy, but several studies have revealed an increase in SGOT &SGPT values in these surgical procedures. SGPT itself occurs due to the procedure of laparoscopy. In the procedure, there is a temporary increase in the pneumoperitoneum, the pressure on the pneumoperitoneum and its duration affect the severity of ischemia by causing an increase in this liver enzyme. Among several studies, one of them revealed that at 48 hours after laparoscopic cholecystectomy surgery an enzyme increase. Objective. The purpose of the study, this research was conducted to see the changes in SGOT & SGPT values in laparoscopic cholecystectomy surgery. Method. This research method is analytic with cross sectional study design conducted at North Sumatera University Hospital. This research was conducted by looking at secondary data, namely the medical record of patients with gallstones who underwent laparoscopic cholecystectomy surgery from January 2019 to November 2019. The sample was selected by using total sampling method. Data were then analyzed using statistical application software. The number of samples was 45 samples with a diagnosis of gallstones who performed laparoscopic cholecystectomy. Results. Wilcoxon test results showed a significant change between SGOT and SGPT levels before performing operations with SGOT and SGPT levels after surgery with p=0.000 (p<0,05). Conclusion. There are changes in SGOT & SGPT in laparoscopic cholecystectomy.

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References

1. Lalisang, T. J. M. 2012. Kolesistektomi Laparoskopi. Sagung Seto, Jakarta.
2. Lesmana, L. A. 2015, Penyakit Batu Empedu dalam Buku Ajar Ilmu Penyakit Dalam. 4th Ed. Pusat Penerbitan Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia, Jakarta.
3. Tjiu, V. V. 2014. Perubahan Serum Transaminase Post-Operatif Pasien Kolelitiasis yang Menjalani Kolesistektomi Laparoskopi dan Kolesistektomi Terbuka di RSUP H. Adam Malik Tahun 2014. Fakultas Kedokteran. Universitas Sumatera Utara. Skripsi.
4. Erylimaz, H. B., D. Memis, A. Sezer, dan M. T. Inal. 2012. ‘The Effects of Different Insufflation Pressures on Liver Functions Assessed with LiMON on Patien Undergoing Laparoscopic Cholecystectomy’. The Scientific World Journal 2012 : 172 – 575.
5. Singh, K., D. Singh, A. Chandra, M. Alam, P. Agrawal. 2019. ‘Liver Function and Serum Amylase Alterations Following Laparoscopic and Open Cholecystectomy
6. Dani dan Susilo, L. 2012, Karakteristik Pasien Cholelithiasis di Rumah Sakit Immanuel Bandung Periode 1 Januari 2012–31 Desember 2012. Fakultas Kedokteran Universitas Kristen.
7. Stinton, L. M dan E. A. Shaffer. 2012. ‘Epidemiology of Gallbladder Disease: Cholelithiasis and Cancer’. Gut and Liver 6(2): 172 – 187.
8. Dahlan, M.S. 2017, Statistik untuk kedokteran dan kesehatan. 3th Ed. Salemba Medika, Jakarta.

Published

2019-04-20

How to Cite

1.
Aziizah Gita, Muhar AM. Changes In Glutamic Oxaloacetic Transaminase Serum (SGOT) and Glutamic Pyruvic Transaminase Serum (SGPT) Value In Laparoscopic Cholecystectomy Patient at USU Hospital. Sumat. Med. J. [Internet]. 2019Apr.20 [cited 2024May4];3(2). Available from: https://talenta.usu.ac.id/smj/article/view/3273

Issue

Vol. 3 No. 2 (2020): Sumatera Medical Journal (SUMEJ)

Section

Research Article

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