Correlation of Platelet-Lymphocyte Ratio (PLR) and Contrast-Induced Nephropathy (CIN) in Patients with ST-Segment Elevation Myocardial Infarction (STEMI) Undergoing Primary Percutaneous Coronary Intervention (PCI)
DOI:
https://doi.org/10.32734/sumej.v4i2.5836Keywords:
ACS, STEMI, platelet lymphocyte ratio, primary PCIAbstract
Acute Coronary Syndrome (ACS) is a series of clinical disorders caused by acute ischemic heart disease. The clinical spectrum of ACS is unstable angina pectoris (UAP), non ST segment elevation myocardial infarction (NSTEMI) and ST segment elevation myocardial infarction (STEMI). Inflammation occurs from the early stages of atheroma formation to plaque rupture and thrombosis. Thrombocytosis and lymphopenia are associated with the degree of systemic inflammation and the platelet lymphocyte ratio (PLR) is a new marker involving both hematological indices. ST segment elevation myocardial infarction is a type of acute myocardial infarction with high mortality. Management of STEMI patients is carried out with reperfusion therapy consisting of primary percutaneous coronary intervention (PCI) and fibrinolytics. Contrast-induced nephropathy is a serious complication of angiograph procedures that results from administration of contrast media.
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References
Antman EM, Braunwald E. St-segment elevation myocardial infarction. Dalam: Loscalzo J (ed). Harrison’s cardiovascular medicine. New York: McGraw-Hill Medical, pp: 395-413.2010.
Thygesen, Kristian et al. “Third universal definition of myocardial infarction.” European heart journal vol. 33,20 (2012): 2551-67. doi:10.1093/eurheartj/ehs184
Black,J.M., dan Hawks,J.H. Medical Surgical Nursing. New York. Elsevier.2005.
Perhimpunan Dokter Spesialis Kardiovaskular Indonesia 2018, Pedoman tatalaksana Sindrom Koroner Akut. 3rd edn. Edited by Centra Communications. Jakarta.
Goldenberg I, Matetzky S. Nephropathy induced by contrast media: Pathogenesis, risk factors and preventive strategies. CMAJ. 2005;172:1461–71.
Acikgoz, et al. “Platelet to Lymphocyte Ratio Is Associated with Contrast Induced Nephropathy after Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction Section.” Annals of Medical Research, 2019, p. 1., doi:10.5455/annalsmedres.2019.02.087.
Sun, Xi peng, and Jing Li. “Platelet to Lymphocyte Ratio Predicts Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.” SAGE, 2017.
Romano G, Briguori C, Quintavalle C, Zanca C, Rivera NV, Colombo A, et al. Contrast agents and renal cell apoptosis. Eur Heart J. 2008;29:2569–76
Demircelik, Muhammed Bora, et al. “Association between Platelet-to-Lymphocyte Ratio and Contrast-Induced Nephropathy in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndrome.” Cardiorenal Medicine, vol. 5, no. 2, 2015, pp. 96–104., doi:10.1159/000371496.
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