The Effect of Torbangun Leaves Tea on Msg-induced Fetal Develop-ment Disorder in Mice

Authors

  • Sufitni M.Kes Universitas Sumatera Utara
  • Lita Feriyawati Universitas Sumatera Utara
  • Yunita Sari Pane Universitas Sumatera Utara
  • Aznan Lelo Universitas Sumatera Utara

DOI:

https://doi.org/10.32734/sumej.v2i1.717

Keywords:

Fetal Development Disorder, Monosodium Glutamate (MSG), Mice, Pregnancy

Abstract

The safety of MSG on the fetus has not been confirmed yet. The objective of this research is to determine the effect of tea of torbangun leaves on fetal development disorder of mice. The present study is experimental with a Completely Randomized Design (CRD). Data obtained were then analyzed by ANOVA, with p<0,05 as the level of significant.   The comparison of mean values ± SEM increase number of live fetuses  group C1-T1 (4,60 ± 0,93; 11,40 ± 0,87), p=0,018. The comparison of mean values ± SEM decrease number of embryo re-sorption percentage group C0-C1 (00,00 ± 00,00; 36,74 ± 15,13), group C1-C2 (36,74 ± 15,13; 00,00 ± 0,00), group C1-T1 (36,74 ± 15,13; 00,00 ± 0,00), and group C1-T2 (36,74 ± 15,13; 15,00 ± 22,36), p=0,020. This study concluded that T1 group is giving the best effect on increasing life fetuses and decreasing embryo re-sorption percentage.

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Author Biographies

Sufitni M.Kes, Universitas Sumatera Utara

Department of Anatomy, Medical School, Faculty of Medicine Universitas Sumatera Utara

Lita Feriyawati, Universitas Sumatera Utara

Department of Anatomy, Medical School, Faculty of Medicine Universitas Sumatera Utara

Yunita Sari Pane, Universitas Sumatera Utara

Department of Pharmacology and Therapeutics, Medical School, Faculty of Medicine Universitas Sumatera Utara

Aznan Lelo, Universitas Sumatera Utara

Department of Pharmacology and Therapeutics, Medical School, Faculty of Medicine Universitas Sumatera Utara

Published

2019-01-30

How to Cite

1.
M.Kes S, Feriyawati L, Pane YS, Lelo A. The Effect of Torbangun Leaves Tea on Msg-induced Fetal Develop-ment Disorder in Mice. Sumat. Med. J. [Internet]. 2019Jan.30 [cited 2024Mar.29];2(1):34 - 38. Available from: https://talenta.usu.ac.id/smj/article/view/717