Diagnosis Tiroiditis Hashimoto pada Seorang Wanita dengan Hipotiroidisme Subklinis dan Trombositopenia: Laporan Kasus

Authors

  • Devi Aulia Cahyani Departemen Penyakit Dalam RSUD Genteng Banyuwangi, Jawa Timur, Indonesia, 68465
  • Annisa Nur Masita Puskesmas Mangli, Jember, Jawa Timur, Indonesia, 68175

DOI:

https://doi.org/10.32734/scripta.v6i1.15187

Keywords:

trombositopenia, Hashimoto’s Thyroiditis, Thrombocytopenia, Subclinical Hypothyroidism, Tiroidits Hashimoto, Hipotiroidisme Subklinis

Abstract

Background: Hashimoto’s Thyroiditis (TH) is a variety of autoimmune thyroid disorders. It discovered incidentally, asymptomatic and generally normal thyroid profile, therefore it might adventurous to be diagnosed. Objectives: To describe establishing TH diagnosis in a woman with subclinical hypothyroidism and thrombocytopenia. Case Illustration: A woman, 46 years old, referred fatigue, joints pain and neck lump for about ± a year, physical examination was found diffuse goiter, USG examination was found TIRADS 2, laboratory examination was found thrombocytopenia, euthyroid, anti-TPO 203,8 IU/mL. Discussion: USG was concluded solid lesion visualized typical thyroiditis without FNAB required and anti-TPO results was appropriate with TH predictor>121,0 IU/ml. Numerous of studies showed TH which occurred with secondary immune thrombocytopenia. Conclusion: Subclinical hypothyroidism which presented diffuse goiter and higher normal TSH required USG and anti-TPO examination for established its diagnosis. Persistent thrombocytopenia might be suspected as autoimmune thyroid disorder especially whether presented goiter.

Latar Belakang: Tiroiditis Hashimoto (TH) merupakan penyakit autoimun kelenjar tiroid. Penyakit ini ditemukan secara insidental, asimptomatik dan umumnya profil tiroid dalam batas normal sehingga mendiagnosisnya menjadi tantangan tersendiri. Tujuan: Menjelaskan penegakan diagnosis TH pada wanita dengan hipotiroidisme subklinis dan trombositopenia. Ilustrasi Kasus: Seorang wanita 46 tahun mengeluhkan cepat lelah, linu, benjolan leher selama ±1 tahun, pemeriksaan fisik didapatkan goiter difus, pemeriksaan USG didapatkan TIRADS 2, pemeriksaan laboratorium didapatkan trombositopenia, eutiroid, anti-TPO 203,8 IU/mL. Pembahasan: USG disimpulkan lesi solid mengesankan tiroiditis tanpa perlu FNAB dan anti-TPO sesuai dengan prediktor TH >121,0 IU/ml. Banyak studi menyebutkan TH yang disertai immune thrombocytopenia sekunder. Kesimpulan: Hipotiroidisme subklinis berupa goiter difus dan TSH sedikit meningkat perlu dilakukan USG dan anti-TPO untuk penegakan diagnosisnya. Trombositopenia persisten dapat dicurigai penyakit autoimun tiroid terutama bila terdapat goiter.

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Published

2024-08-15

How to Cite

1.
Cahyani DA, Masita AN. Diagnosis Tiroiditis Hashimoto pada Seorang Wanita dengan Hipotiroidisme Subklinis dan Trombositopenia: Laporan Kasus. SCRIPTA SCORE Sci Med J. [Internet]. 2024Aug.15 [cited 2024Oct.11];6(1):80-3. Available from: https://talenta.usu.ac.id/scripta/article/view/15187