Effects of 1% and 3% Mobe Leaf Extract Gel on Socket Wound Healing after Tooth Extraction

Efek Gel Ekstrak Daun Mobe 1% dan 3% pada Penyembuhan Luka Soket Pasca Pencabutan Gigi

Authors

  • Olivia Avriyanti Hanafiah Faculty of Dentistry, Universitas Sumatera Utara
  • Denny Satria Faculty of Dentistry, Universitas Sumatera Utara
  • Avi Syafitri Faculty of Dentistry, Universitas Sumatera Utara

DOI:

https://doi.org/10.32734/dentika.v24i1.5327

Keywords:

mobe leaf, tooth extraction, wound healing, fibroblast

Abstract

Tooth extraction is a process of removing teeth from the alveolar bone. In wound healing, fibroblast are very important cells. The main purpose of this study was to determine the effect of mobe leaf 1% and 3% extract gel (Artocarpus lakoocha) on fibroblast proliferation in post extraction tooth socket wound healing. This research used 16 samples of wistar rats, divided into 4 groups, a positive control group, a negative control group and a 1% and 3% mobe leaf extract gel group. The left mandibular incisors were extracted, then 1% and 3% gels of mobe leaf extract were applied on day 1 to day 7. Data analysis was calculated using the Kruskal-Wallis test on clinical data and one way ANOVA test for microscopic. The result of the socket wound healing activity test for a good concentration of mobe leaf extract gel was 3%. This research shows significant resultith p-value of 0.018 (< 0.05) on the closure of the socket wound clinically which means the closure of the wound accelerates because of the mobe leaf 3% extract gel treatment. The distance of fibroblast on microscopically shows significant resultith a p-value of 0.002 (< 0.05), which means that there was an enlargement of the distance fibroblast at the socket wound closure with application of mobe leaf 3% extract gel. From the results of the study it can be concluded that mobe leaf 3% extract gel has the best ability to show acceleration the closure of the socket wound either clinically or microscopically.

Downloads

Download data is not yet available.

Author Biographies

Olivia Avriyanti Hanafiah, Faculty of Dentistry, Universitas Sumatera Utara

Department of Oral and Maxillofacial Surgery

Denny Satria, Faculty of Dentistry, Universitas Sumatera Utara

Department of Oral and Maxillofacial Surgery

Avi Syafitri, Faculty of Dentistry, Universitas Sumatera Utara

Department of Oral and Maxillofacial Surgery

Published

2021-07-06

How to Cite

Hanafiah, O. A., Satria, D. ., & Avi Syafitri. (2021). Effects of 1% and 3% Mobe Leaf Extract Gel on Socket Wound Healing after Tooth Extraction: Efek Gel Ekstrak Daun Mobe 1% dan 3% pada Penyembuhan Luka Soket Pasca Pencabutan Gigi. Dentika: Dental Journal, 24(1), 1-5. https://doi.org/10.32734/dentika.v24i1.5327