The Comparison of Er α Expression Between Endometriosis with No Endometriosis

Authors

  • D. Irsat Syafardi Universitas Sumatera Utara
  • Hendry Salim Siregar Universitas Sumatera Utara
  • Yostoto B Kaban Universitas Sumatera Utara
  • Edy Ardiansyah Universitas Sumatera Utara

DOI:

https://doi.org/10.32734/sumej.v2i1.714

Keywords:

Estrogen α receptor, endometriosis, normal endometrium

Abstract

Estrogen receptors (ER) play an important role in mediating action. The ER α has a higher affinity for estrogen and the dominant form of the normal endometrium. A cross-sectional study from an ectopic  tissue of endo-metriosis and normal was examined for immunohistochemistry. This research was conducted from November 2015 until the sample complete. The analysis was performed using Fisher Exact test, p <0.05 was considered to any difference of estrogen alpha receptor expression between endometriosis patients with no endometriosis. REα is more dominant in normal endometrium, whereas in the case of endometriosis in the presence of many negative expression of REα then the assumption that REβ is a receptor that many encountered. There is a dif-ference in the expression of REα between endometriosis with no endometriosis.

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Author Biographies

D. Irsat Syafardi, Universitas Sumatera Utara

Department of Obstetrics Gynecology, Faculty of Medicine Universitas Sumatera Utara

Hendry Salim Siregar, Universitas Sumatera Utara

Department of Obstetrics Gynecology, Faculty of Medicine Universitas Sumatera Utara

Yostoto B Kaban, Universitas Sumatera Utara

Department of Obstetrics Gynecology, Faculty of Medicine Universitas Sumatera Utara

Edy Ardiansyah, Universitas Sumatera Utara

Department of Obstetrics Gynecology, Faculty of Medicine Universitas Sumatera Utara

Published

2019-01-30

How to Cite

1.
Syafardi DI, Siregar HS, Kaban YB, Ardiansyah E. The Comparison of Er α Expression Between Endometriosis with No Endometriosis. Sumat. Med. J. [Internet]. 2019Jan.30 [cited 2024Mar.29];2(1):15 - 21. Available from: https://talenta.usu.ac.id/smj/article/view/714

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